è The administration of the anticancer agent can be delayed for a
maximum of 2 weeks, and if the delay exceeds 3 weeks, consideration should be
given to adjusting the cisplatin dosage. Chemotherapy can be initiated if the
following criteria are satisfied. If any of these criteria are not met, the
administration of the anticancer agent should be postponed.
Within 7 days prior to anticancer agent administration -
Hematological findings.
[1] Neutrophil: ≥1,000/mm³, Grade 2 or higher
[2] Platelet count: ≥75,000/mm³, Grade 1 or higher
[3] SGOT: ≤100 U/L
[4] SGPT: ≤100 U/L
[5] Total bilirubin: ≤2.0
mg/dL
[6] Creatinine: ≤1.2 mg/dL
(However, for the first cycle of chemotherapy,
results up to within 4 weeks can be utilized.)
One day prior to chemotherapy drug administration.
[1] No peripheral motor or
sensory neuropathy of Grade 2 or higher.
[2] No auditory impairment of
grade 2 or higher
[3] No diarrhea of grade 3 or
higher.
[4] No nausea or vomiting or
loss of appetite of grade 3 or higher.
[5] No
fever due to infection exceeding 38℃
[6] No non-hematologic toxicity
of grade 3 or higher related to treatment.